Cacti Peyote (Lophophora williamsii, contains mescaline), San Pedro cactus (Echinopsis pachanoi), Peruvian Torch cactus (Echinopsis peruviana).
Plants and seeds Ayahuasca vine (Banisteriopsis caapi, contains harmala alkaloids) — usually combined with a DMT-containing plant such as Psychotria viridis (chacruna) or Diplopterys cabrerana; Salvia divinorum (salvinorin A); Datura species (thorn apple/jimsonweed; tropane alkaloids, highly toxic); Brugmansia (angel’s trumpet); Iboga (Tabernanthe iboga, contains ibogaine); Morning Glory seeds and Hawaiian Baby Woodrose (contain LSA); Kratom (Mitragyna speciosa, an atypical entheogen); Cannabis (regarded as an entheogen in some traditions); Wild rue (Peganum harmala, contains harmala alkaloids, also used as an MAO inhibitor in ayahuasca-like brews).
Toads/animals Bufo alvarius / Incilius alvarius (Colorado River Toad) — skin secretion contains 5-MeO-DMT.
Synthetic or semi-synthetic substances (with a spiritual/entheogenic tradition of use) LSD (lysergic acid diethylamide, derived from the ergot alkaloid), Psilocybin (also available synthetically), Mescaline (also synthetic), DMT (N,N-dimethyltryptamine, also synthetic outside of ayahuasca), 5-MeO-DMT, Ibogaine (also isolated/synthetic), MDMA (sometimes mentioned in a therapeutic/ritual context, though chemically not a classic entheogen).
Other/traditionally smoked or snuffed mixtures Tobacco in shamanic context (Nicotiana rustica), Yopo/Cohoba snuff (Anadenanthera seeds, contain DMT and bufotenine).